Wuhan Coronavirus

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Rack

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Stay healthy and inquisitive my friends...it never hurts to question as long as we are complying. Just so you know, I'm NOT suggesting that we shouldn't comply with authorities, we should...BUT that doesn't mean they are above question.
 
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RxCowboy

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Lots of info...can you summarize? Hoping it's good!
Remdisivir shows the most promise, but it isn't on the market yet. Taking it out of orphan drug may actually slow down it's progress to market.

Hydroxy/chloroquine +/- azithro - multiple clinical trials underway. My opinion: we're going to have to treat it like we do chemotherapy trials, collecting data as we treat.

Vit c - a couple of trials underway using MEGA doses, like 24 grams per day or more of IV vit c, for patients in ICU with ARDS. I've already seen morons on Facebook "See, taking Vit C will make me immune!" Even IF it increases white cell count, which there is no data, your WBCs have never seen COVID-19 before and don't know what to do.

Lopinavir/ritonavir - trials underway, no evidence of efficacy yet.

Neuramidase inhibitors (oseltamivir) - doesn't work

Azithro alone - insufficient evidence

Corticosteroids - recommended they NOT be used unless you have another reason. Suppressing the immune system is bad, y'all.

ACE inhibitors and ARBs - ACC/AHA recommends not stopping them. Trials are underway to assess if they limit organ failure.

Ibuprofen - NO, DON'T TAKE IT! Not much actual evidence, but, dang, who wants to take that chance?

Baloxavir - doesn't work.
 

Rack

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Hospitals in Maryland considering "universal DNR". That is, involuntary DNR.

https://www.washingtonpost.com/heal...QQQT1xoHVzAW-s6fP-O8_1nHqYW2_1Qhv-bfHz_WOTYGA

@Rack where they considering that last March?
I'm not trying to sensationalize this...I'm just asking questions about the data and WHY wouldn't one use statistical comparisons of past years when arguing space issues in ICU's? Just seems like common sense to include that.

Btw, prayers for Maryland and other hard hit areas as well as the entire nation. May God keep us safe, healthy and FREE. God Bless us Every One!
 

Binman4OSU

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Stupid about AGW!!
Remdisivir shows the most promise, but it isn't on the market yet. Taking it out of orphan drug may actually slow down it's progress to market.

Hydroxy/chloroquine +/- azithro - multiple clinical trials underway. My opinion: we're going to have to treat it like we do chemotherapy trials, collecting data as we treat.

Vit c - a couple of trials underway using MEGA doses, like 24 grams per day or more of IV vit c, for patients in ICU with ARDS. I've already seen morons on Facebook "See, taking Vit C will make me immune!" Even IF it increases white cell count, which there is no data, your WBCs have never seen COVID-19 before and don't know what to do.

Lopinavir/ritonavir - trials underway, no evidence of efficacy yet.

Neuramidase inhibitors (oseltamivir) - doesn't work

Azithro alone - insufficient evidence

Corticosteroids - recommended they NOT be used unless you have another reason. Suppressing the immune system is bad, y'all.

ACE inhibitors and ARBs - ACC/AHA recommends not stopping them. Trials are underway to assess if they limit organ failure.

Ibuprofen - NO, DON'T TAKE IT! Not much actual evidence, but, dang, who wants to take that chance?

Baloxavir - doesn't work.
I was reading some of the very positive outcomes using Remdisivir yesterday
 

RxCowboy

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I'm not trying to sensationalize this...I'm just asking questions about the data and WHY wouldn't one use statistical comparisons of past years when arguing space issues in ICU's? Just seems like common sense to include that.

Btw, prayers for Maryland and other hard hit areas as well as the entire nation. May God keep us safe, healthy and FREE. God Bless us Every One!
Because hospital conditions change in a year. Beds open, beds close... staffing levels change. None of that matters. What matters is what it looks like today and what it might look like tomorrow.
 

Rack

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Because hospital conditions change in a year. Beds open, beds close... staffing levels change. None of that matters. What matters is what it looks like today and what it might look like tomorrow.
Ok, sure, but they left a hole in their argument about space being a premium in ICU and that was my point. They could have easily filled that hole and used information from past years and compared and even explained away the differences being because of bed clearing if it wasn't favorable...Bottom line, that article is being used all over town and WILL ratchet up the fear levels...
 

RxCowboy

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Ok, sure, but they left a hole in their argument about space being a premium in ICU and that was my point. They could have easily filled that hole and used information from past years and compared and even explained away the differences being because of bed clearing if it wasn't favorable...Bottom line, that article is being used all over town and WILL ratchet up the fear levels...
Oy... okay.
 

State

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This is true...they have postponed all "elective" procedures and made room in the hospitals...they currently, it is my understanding, still have that "room." This is why January and February numbers comparable to last year would be key in those stats...because those bigtime changes started happening in early March so those numbers, you are correct, are likely skewed. For this I would only be interested in Oklahoma numbers because I feel the Tulsa World Article is somewhat misleading and fear mongering.
This is something I don't agree with about the government mandated orders. Elective procedures shouldn't have all been cancelled. I understand part of it was likely that sometimes those procedures have complications and lead to more serious treatment requirements. We probably have lots of Dr's sitting on their nuts now waiting to be called into service for Covid-19 who could be doing good with their normal procedures. I think this is something hospitals likely could have managed on their own to make the best use of their resources, and they still may have made that decision, but they're better equipped to do so.
 

osupsycho

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Ok, sure, but they left a hole in their argument about space being a premium in ICU and that was my point. They could have easily filled that hole and used information from past years and compared and even explained away the differences being because of bed clearing if it wasn't favorable...Bottom line, that article is being used all over town and WILL ratchet up the fear levels...
Yeah but that is what the media does...
 

Binman4OSU

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US surpasses Italy with the number to cases reported. 2nd only to China in total # of reported cases


US New Cases 6,858 and 53 new deaths
75,069 total cases, 1,080 total deaths, 1,857 in serious or critical condition, 1,863 total recovered
 

osupsycho

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US surpasses Italy with the number to cases reported. 2nd only to China in total # of reported cases


US New Cases 6,858 and 53 new deaths
75,069 total cases, 1,080 total deaths, 1,857 in serious or critical condition, 1,863 total recovered
So they are not reporting hospitalizations?
 

sc5mu93

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US surpasses Italy with the number to cases reported. 2nd only to China in total # of reported cases


US New Cases 6,858 and 53 new deaths
75,069 total cases, 1,080 total deaths, 1,857 in serious or critical condition, 1,863 total recovered
The US *will* surpass China for 2 reasons 1) a reasonably accountable (e.g. not state controlled) press reporting reasonably accurate numbers and 2) Human rights.
 

RxCowboy

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@Rack this is why last year doesn't matter:

Six months of supplies gone in a week
Georgia Gov. Brian Kemp had committed additional resources to make 26 beds available in a different facility, Albany officials said Wednesday.

The health system's most "severely impacted" hospital is in Albany, Steiner said in a statement.

The state will soon be bringing in more ventilators and personal protective equipment, Dorough said.